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3,4 In addition, a consensus document has recently been published to implement the calculation of the eGFR in Spanish laboratories.

The National Kidney Foundation KDOQI guidelines, as well as a recent declaration by the AHA, recommend calculating the estimated GFR (eGFR) in at-risk populations. This has led to growing interest in determining the epidemiology of CKD in the general population, as well as in at-risk populations.

The rise in the prevalence of CKD in the western world can be explained by the progressive aging of the population and the increases in diabetes mellitus (DM), hypertension, and obesity. A reduction in glomerular filtration rate (GFR) has been related with an increase in the risk of cardiovascular complications and greater morbidity and mortality. Chronic kidney disease (CKD) is a major health care problem due to its associated high morbidity and mortality, increasing prevalence, and elevated costs.